4-S is genuinely a bad stage, while most special stages ARE more difficult than normal ones, this one cranks it up to 12. Featuring an autoscroller WHILE being chased! If that wasn't enough, it also speeds up a lot near the end. You also have to multi-task well to get everything.
If this game ever gets a Switch/Switch 2 port/remaster, I'd like to see the Yoshi-creation tool in the 3DS version to be added to it. (Alongside maybe the updated Amiibo compatibility?)